Degrons in cancer
Supplementary Material
Bálint Mészáros1,* , Manjeet
Kumar2,*, Toby
Gibson2, Bora
Uyar3 and Zsuzsanna Dosztányi4
1. Institute of Enzymology, Research Centre for Natural Sciences, Hungarian Academy of
Sciences, 2 Magyar Tudósok krt, Budapest H-1117, Hungary
2. EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg,
Germany
3. Bioinformatics Platform, The Berlin Institute for Medical Systems Biology, Max-Delbrück Center for
Molecular Medicine, Robert-Rössle-Strasse 10, 13125 Berlin, Germany
4. MTA-ELTE Lendület Bioinformatics Research
Group, Department of Biochemistry, Eötvös Loránd University, Pázmány Péter stny 1/c, Budapest H-1117, Hungary
*
These authors contributed equally to this work and both should be considered first authors.
Science Signalling in press
Table 1. Known degron motifs collected from the ELM database and manual curation
Table 2. Target recognition subunits of E3 ligases