AURKA
AURKA | chr20 |
O14965
|
AURKA | Aurora kinase A |
Sequence
Complexity
Exons
OMIM Disease Mutations
Polymorphisms
Cancer Mutations
Domains
Structure
Disorder
Motifs
Modifications
Features
Conservation
Position
Sequence
Complexity - SEG
Complexity - DUST
Complexity - TRF
Exons
OMIM Disease Mutations
Polymorphisms
Cancer Mutations
Cancer Indels
Cancer Frameshift/Nonsense
Domains
Structure
Exp disorder
Exp order
Disorder
Manual instances
Scansite
Predicted
PhosphoElm Modifications
Phosphosite+ Modifications
Uniprot Modifications
Regions of interest
Binding regions
PhastCons
PhyloP
ScoreCons Relevant
ScoreCons All
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|1
|51
|101
|151
|201
|251
|301
|351
|401
M
D
R
S
K
E
N
C
I
S
G
P
V
K
A
T
A
P
V
G
G
P
K
R
V
L
V
T
Q
Q
F
P
C
Q
N
P
L
P
V
N
S
G
Q
A
Q
R
V
L
C
P
S
N
S
S
Q
R
I
P
L
Q
A
Q
K
L
V
S
S
H
K
P
V
Q
N
Q
K
Q
K
Q
L
Q
A
T
S
V
P
H
P
V
S
R
P
L
N
N
T
Q
K
S
K
Q
P
L
P
S
A
P
E
N
N
P
E
E
E
L
A
S
K
Q
K
N
E
E
S
K
K
R
Q
W
A
L
E
D
F
E
I
G
R
P
L
G
K
G
K
F
G
N
V
Y
L
A
R
E
K
Q
S
K
F
I
L
A
L
K
V
L
F
K
A
Q
L
E
K
A
G
V
E
H
Q
L
R
R
E
V
E
I
Q
S
H
L
R
H
P
N
I
L
R
L
Y
G
Y
F
H
D
A
T
R
V
Y
L
I
L
E
Y
A
P
L
G
T
V
Y
R
E
L
Q
K
L
S
K
F
D
E
Q
R
T
A
T
Y
I
T
E
L
A
N
A
L
S
Y
C
H
S
K
R
V
I
H
R
D
I
K
P
E
N
L
L
L
G
S
A
G
E
L
K
I
A
D
F
G
W
S
V
H
A
P
S
S
R
R
T
T
L
C
G
T
L
D
Y
L
P
P
E
M
I
E
G
R
M
H
D
E
K
V
D
L
W
S
L
G
V
L
C
Y
E
F
L
V
G
K
P
P
F
E
A
N
T
Y
Q
E
T
Y
K
R
I
S
R
V
E
F
T
F
P
D
F
V
T
E
G
A
R
D
L
I
S
R
L
L
K
H
N
P
S
Q
R
P
M
L
R
E
V
L
E
H
P
W
I
T
A
N
S
S
K
P
S
N
C
Q
N
K
E
S
A
S
K
Q
S
Pkinase
Other
Aurora A
Erk1 Binding
Protein Kinase A
DEG_APCC_DBOX_1
DEG_APCC_KENBOX_2
DEG_Nend_UBRbox_2
S
S
S
S
Y
S
S
S
T
T
S
S
S
S
T
T
S
S
S
S
K
Y
T
Y
Y
Y
S
S
S
S
T
T
T
Y
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
T
T
S
Activation segment
K
K
D