CDKN1A


    CDKN1A   |   chr6   |   P38936   |   CDKN1A   |   Cyclin-dependent kinase inhibitor 1   |  

Sequence Complexity Exons OMIM Disease Mutations Polymorphisms Cancer Mutations Domains Structure Disorder Motifs Modifications Features Conservation


Position
Sequence
Complexity - SEG
Complexity - DUST
Complexity - TRF
Exons
OMIM Disease Mutations
Polymorphisms
Cancer Mutations
Cancer Indels
Cancer Frameshift/Nonsense
Domains
Structure
Exp disorder
Exp order
Disorder
ELM instances
Manual instances
Switches
Modification switches
Scansite
Predicted
PhosphoElm Modifications
Phosphosite+ Modifications
Uniprot Modifications
Regions of interest
Motifs
PhastCons
PhyloP
ScoreCons Relevant
ScoreCons All
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|1
|51
|101
|151
M
S
E
P
A
G
D
V
R
Q
N
P
C
G
S
K
A
C
R
R
L
F
G
P
V
D
S
E
Q
L
S
R
D
C
D
A
L
M
A
G
C
I
Q
E
A
R
E
R
W
N
F
D
F
V
T
E
T
P
L
E
G
D
F
A
W
E
R
V
R
G
L
G
L
P
K
L
Y
L
P
T
G
P
R
R
G
R
D
E
L
G
G
G
R
R
P
G
T
S
P
A
L
L
Q
G
T
A
E
E
D
H
V
D
L
S
L
S
C
T
L
V
P
R
S
G
E
Q
A
E
G
S
P
G
G
P
G
D
S
Q
G
R
K
R
R
Q
T
S
M
T
D
F
Y
H
S
K
R
R
L
I
F
S
K
R
K
P
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
CDI
D-box
Aurora A
Calmodulin dependent Kinase 2
AMP_Kinase
DEG_CRL4_CDT2_1
DEG_CRL4_CDT2_1
DEG_CRL4_CDT2_2
DEG_CRL4_CDT2_2
T
T
T
S
S
S
S
S
S
S
S
T
T
T
T
T
S
S
S
S
S
K
K
T
S
S
K
K
R
K
K
K
K
K
S
T
K
T
S
S
T
S
S
T
S
S
Required for binding cyclins
Required for binding CDKs
PIP-box K+4 motif
Nuclear localization signal