CRBN
CRBN | chr3 |
Q96SW2
|
CRBN | Protein cereblon |
Sequence
Complexity
Exons
OMIM Disease Mutations
Polymorphisms
Cancer Mutations
Domains
Structure
Disorder
Motifs
Modifications
Features
Conservation
Position
Sequence
Complexity - SEG
Complexity - DUST
Complexity - TRF
Exons
OMIM Disease Mutations
Polymorphisms
Cancer Mutations
Cancer Indels
Cancer Frameshift/Nonsense
Domains
Structure
Exp disorder
Exp order
Disorder
Scansite
Predicted
PhosphoElm Modifications
Phosphosite+ Modifications
Uniprot Modifications
Regions of interest
PhastCons
PhyloP
ScoreCons Relevant
ScoreCons All
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|1
|51
|101
|151
|201
|251
|301
|351
|401
M
A
G
E
G
D
Q
Q
D
A
A
H
N
M
G
N
H
L
P
L
L
P
A
E
S
E
E
E
D
E
M
E
V
E
D
Q
D
S
K
E
A
K
K
P
N
I
I
N
F
D
T
S
L
P
T
S
H
T
Y
L
G
A
D
M
E
E
F
H
G
R
T
L
H
D
D
D
S
C
Q
V
I
P
V
L
P
Q
V
M
M
I
L
I
P
G
Q
T
L
P
L
Q
L
F
H
P
Q
E
V
S
M
V
R
N
L
I
Q
K
D
R
T
F
A
V
L
A
Y
S
N
V
Q
E
R
E
A
Q
F
G
T
T
A
E
I
Y
A
Y
R
E
E
Q
D
F
G
I
E
I
V
K
V
K
A
I
G
R
Q
R
F
K
V
L
E
L
R
T
Q
S
D
G
I
Q
Q
A
K
V
Q
I
L
P
E
C
V
L
P
S
T
M
S
A
V
Q
L
E
S
L
N
K
C
Q
I
F
P
S
K
P
V
S
R
E
D
Q
C
S
Y
K
W
W
Q
K
Y
Q
K
R
K
F
H
C
A
N
L
T
S
W
P
R
W
L
Y
S
L
Y
D
A
E
T
L
M
D
R
I
K
K
Q
L
R
E
W
D
E
N
L
K
D
D
S
L
P
S
N
P
I
D
F
S
Y
R
V
A
A
C
L
P
I
D
D
V
L
R
I
Q
L
L
K
I
G
S
A
I
Q
R
L
R
C
E
L
D
I
M
N
K
C
T
S
L
C
C
K
Q
C
Q
E
T
E
I
T
T
K
N
E
I
F
S
L
S
L
C
G
P
M
A
A
Y
V
N
P
H
G
Y
V
H
E
T
L
T
V
Y
K
A
C
N
L
N
L
I
G
R
P
S
T
E
H
S
W
F
P
G
Y
A
W
T
V
A
Q
C
K
I
C
A
S
H
I
G
W
K
F
T
A
T
K
K
D
M
S
P
Q
K
F
W
G
L
T
R
S
A
L
L
P
T
I
P
D
T
E
D
E
I
S
P
D
K
V
I
L
C
L
LON_substr_bdg
Yippee-Mis18
AMP_Kinase
DEG_APCC_DBOX_1
DEG_APCC_DBOX_1
K
K
S
K
S
K
S
K
S
Thalidomide binding domain
Thalidomide binding