MTOR
MTOR | chr1 |
P42345
|
MTOR | Serine/threonine-protein kinase mTOR |
Sequence
Complexity
Exons
OMIM Disease Mutations
Polymorphisms
Cancer Mutations
Domains
Structure
Disorder
Motifs
Modifications
Features
Conservation
Position
Significantly mutated
Sequence
Complexity - SEG
Complexity - DUST
Complexity - TRF
Exons
OMIM Disease Mutations
Polymorphisms
Cancer Mutations
Cancer Indels
Cancer Frameshift/Nonsense
Domains
Structure
Exp disorder
Exp order
Disorder
Manual instances
Scansite
Predicted
PhosphoElm Modifications
Phosphosite+ Modifications
Uniprot Modifications
Regions of interest
PhastCons
PhyloP
ScoreCons Relevant
ScoreCons All
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|1
|51
|101
|151
|201
|251
|301
|351
|401
|451
|501
|551
|601
|651
|701
|751
|801
|851
|901
|951
|1001
|1051
|1101
|1151
|1201
|1251
|1301
|1351
|1401
|1451
|1501
|1551
|1601
|1651
|1701
|1751
|1801
|1851
|1901
|1951
|2001
|2051
|2101
|2151
|2201
|2251
|2301
|2351
|2401
|2451
|2501
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Y
I
G
W
C
P
F
W
DUF3385
FAT
Rapamycin_bind
PI3_PI4_kinase
FATC
FBW7_predicted
Protein Kinase A
CDK1 motif 2 - [ST]PxxK
PLK1 Kinase
CDK1 motif 1 - [ST]Px[KR]x
PDGFR Kin
Aurora A
PKC mu
Akt Kinase
Aurora A
Insulin Receptor Kinase
Akt Kinase
DEG_APCC_DBOX_1
DEG_APCC_DBOX_1
DEG_MDM2_SWIB_1
DEG_Nend_Nbox_1
DEG_SCF_FBW7_1
DEG_SPOP_SBC_1
DEG_SPOP_SBC_1
T
Y
S
T
S
S
T
Y
K
K
Y
K
K
K
S
T
S
K
S
S
K
K
S
S
T
K
Y
S
S
T
S
T
Y
S
K
S
S
T
K
K
T
T
T
K
S
T
T
S
Y
S
S
T
T
T
S
S
K
T
K
T
S
T
S
K
K
S
S
S
M
S
T
K
S
S
T
T
T
S
S
S
Interaction with NBN
Sufficient for interaction with the FKBP1A/rapamycin complex
Interaction with MLST8