RNF4


    RNF4   |   chr4   |   P78317   |   RNF4   |   E3 ubiquitin-protein ligase RNF4   |  

Sequence Complexity Exons OMIM Disease Mutations Polymorphisms Cancer Mutations Domains Structure Disorder Motifs Modifications Features Conservation


Position
Sequence
Complexity - SEG
Complexity - DUST
Complexity - TRF
Exons
OMIM Disease Mutations
Polymorphisms
Cancer Mutations
Cancer Indels
Cancer Frameshift/Nonsense
Domains
Structure
Exp disorder
Exp order
Disorder
ELM instances
Scansite
PhosphoElm Modifications
Phosphosite+ Modifications
Uniprot Modifications
Regions of interest
Motifs
PhastCons
PhyloP
ScoreCons Relevant
ScoreCons All
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|1
|51
|101
|151
|201
V
T
R
G
H
E
R
L
R
T
F
D
F
P
A
N
L
G
I
D
H
F
L
F
C
R
K
G
K
A
P
K
S
T
M
S
T
R
K
R
R
G
G
A
I
N
S
R
Q
A
Q
K
R
T
R
E
A
T
S
T
P
E
I
S
L
E
A
E
P
I
E
L
V
E
T
A
G
D
E
I
V
D
L
T
C
E
S
L
E
P
V
V
V
D
L
T
H
N
D
S
V
V
V
S
D
E
R
R
R
P
R
R
N
A
R
R
L
P
Q
D
H
A
D
S
C
V
V
S
S
D
D
E
E
L
S
R
D
R
D
V
Y
V
T
T
H
T
P
R
N
A
R
D
E
G
A
T
G
L
R
P
S
G
T
V
S
C
P
I
C
M
D
G
Y
S
E
I
V
Q
N
G
R
L
I
V
S
T
E
C
G
H
V
F
C
S
Q
C
L
R
D
S
L
K
N
A
N
T
C
P
T
C
R
K
K
I
N
H
K
R
Y
H
P
I
Y
I
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Amphiphysin SH3
Erk1 Binding
S
S
S
S
S
Y
T
K
Y
T
S
S
Required for ubiquitination activity
Mediates interaction with TRPS1
SUMO interaction motif 1
SUMO interaction motif 2
SUMO interaction motif 3