TK1_ENST00000301634


    TK1_ENST00000301634   |   chr17   |   P04183   |   TK1   |   Thymidine kinase, cytosolic   |  

Sequence Complexity Exons OMIM Disease Mutations Polymorphisms Cancer Mutations Domains Structure Disorder Motifs Modifications Features Conservation


Position
Sequence
Complexity - SEG
Complexity - DUST
Complexity - TRF
Exons
OMIM Disease Mutations
Polymorphisms
Cancer Mutations
Cancer Indels
Cancer Frameshift/Nonsense
Domains
Structure
Exp disorder
Exp order
Disorder
Manual instances
Scansite
Predicted
PhosphoElm Modifications
Phosphosite+ Modifications
Uniprot Modifications
Regions of interest
Binding regions
PhastCons
PhyloP
ScoreCons Relevant
ScoreCons All
?
?
?
?
?
?
?
?
?
?
?
?
?
?
?
?
?
?
?
?
?
?
?
?
?
?
?
?
 
|1
|51
|101
|151
|201
M
S
C
I
N
L
P
T
V
L
P
G
S
P
S
K
T
R
G
Q
I
Q
V
I
L
G
P
M
F
S
G
K
S
T
E
L
M
R
R
V
R
R
F
Q
I
A
Q
Y
K
C
L
V
I
K
Y
A
K
D
T
R
Y
S
S
S
F
C
T
H
D
R
N
T
M
E
A
L
P
A
C
L
L
R
D
V
A
Q
E
A
L
G
V
A
V
I
G
I
D
E
G
Q
F
F
P
D
I
V
E
F
C
E
A
M
A
N
A
G
K
T
V
I
V
A
A
L
D
G
T
F
Q
R
K
P
F
G
A
I
L
N
L
V
P
L
A
E
S
V
V
K
L
T
A
V
C
M
E
C
F
R
E
A
A
Y
T
K
R
L
G
T
E
K
E
V
E
V
I
G
G
A
D
K
Y
H
S
V
C
R
L
C
Y
F
K
K
A
S
G
Q
P
A
G
P
D
N
K
E
N
C
P
V
P
G
K
P
G
E
A
V
A
A
R
K
L
F
A
P
Q
Q
I
L
Q
C
S
P
A
N
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
TK
KEN-box
Cdc2 Kinase
Erk D-domain
Cdk5 Kinase
CDK1 motif 1 - [ST]Px[KR]x
DEG_APCC_KENBOX_2
S
S
S
S
K
S
S
K
K
K
Y
S
K
K
K
S
S
S
K
Y
Y
S
S
S
S
Substrate binding
F
Y