TTK
TTK | chr6 |
P33981
|
TTK | Dual specificity protein kinase TTK |
Sequence
Complexity
Exons
OMIM Disease Mutations
Polymorphisms
Cancer Mutations
Domains
Structure
Disorder
Motifs
Modifications
Features
Conservation
Position
Sequence
Complexity - SEG
Complexity - DUST
Complexity - TRF
Exons
OMIM Disease Mutations
Polymorphisms
Cancer Mutations
Cancer Indels
Cancer Frameshift/Nonsense
Domains
Structure
Exp disorder
Exp order
Disorder
Manual instances
Scansite
Predicted
PhosphoElm Modifications
Phosphosite+ Modifications
Uniprot Modifications
Binding regions
PhastCons
PhyloP
ScoreCons Relevant
ScoreCons All
?
?
?
?
?
?
?
?
?
?
?
?
?
?
?
?
?
?
?
?
?
?
?
?
?
?
?
|1
|51
|101
|151
|201
|251
|301
|351
|401
|451
|501
|551
|601
|651
|701
|751
|801
|851
M
E
S
E
D
L
S
G
R
E
L
T
I
D
S
I
M
N
K
V
R
D
I
K
N
K
F
K
N
E
D
L
T
D
E
L
S
L
N
K
I
S
A
D
T
T
D
N
S
G
T
V
N
Q
I
M
M
M
A
N
N
P
E
D
W
L
S
L
L
L
K
L
E
K
N
S
V
P
L
S
D
A
L
L
N
K
L
I
G
R
Y
S
Q
A
I
E
A
L
P
P
D
K
Y
G
Q
N
E
S
F
A
R
I
Q
V
R
F
A
E
L
K
A
I
Q
E
P
D
D
A
R
D
Y
F
Q
M
A
R
A
N
C
K
K
F
A
F
V
H
I
S
F
A
Q
F
E
L
S
Q
G
N
V
K
K
S
K
Q
L
L
Q
K
A
V
E
R
G
A
V
P
L
E
M
L
E
I
A
L
R
N
L
N
L
Q
K
K
Q
L
L
S
E
E
E
K
K
N
L
S
A
S
T
V
L
T
A
Q
E
S
F
S
G
S
L
G
H
L
Q
N
R
N
N
S
C
D
S
R
G
Q
T
T
K
A
R
F
L
Y
G
E
N
M
P
P
Q
D
A
E
I
G
Y
R
N
S
L
R
Q
T
N
K
T
K
Q
S
C
P
F
G
R
V
P
V
N
L
L
N
S
P
D
C
D
V
K
T
D
D
S
V
V
P
C
F
M
K
R
Q
T
S
R
S
E
C
R
D
L
V
V
P
G
S
K
P
S
G
N
D
S
C
E
L
R
N
L
K
S
V
Q
N
S
H
F
K
E
P
L
V
S
D
E
K
S
S
E
L
I
I
T
D
S
I
T
L
K
N
K
T
E
S
S
L
L
A
K
L
E
E
T
K
E
Y
Q
E
P
E
V
P
E
S
N
Q
K
Q
W
Q
S
K
R
K
S
E
C
I
N
Q
N
P
A
A
S
S
N
H
W
Q
I
P
E
L
A
R
K
V
N
T
E
Q
K
H
T
T
F
E
Q
P
V
F
S
V
S
K
Q
S
P
P
I
S
T
S
K
W
F
D
P
K
S
I
C
K
T
P
S
S
N
T
L
D
D
Y
M
S
C
F
R
T
P
V
V
K
N
D
F
P
P
A
C
Q
L
S
T
P
Y
G
Q
P
A
C
F
Q
Q
Q
Q
H
Q
I
L
A
T
P
L
Q
N
L
Q
V
L
A
S
S
S
A
N
E
C
I
S
V
K
G
R
I
Y
S
I
L
K
Q
I
G
S
G
G
S
S
K
V
F
Q
V
L
N
E
K
K
Q
I
Y
A
I
K
Y
V
N
L
E
E
A
D
N
Q
T
L
D
S
Y
R
N
E
I
A
Y
L
N
K
L
Q
Q
H
S
D
K
I
I
R
L
Y
D
Y
E
I
T
D
Q
Y
I
Y
M
V
M
E
C
G
N
I
D
L
N
S
W
L
K
K
K
K
S
I
D
P
W
E
R
K
S
Y
W
K
N
M
L
E
A
V
H
T
I
H
Q
H
G
I
V
H
S
D
L
K
P
A
N
F
L
I
V
D
G
M
L
K
L
I
D
F
G
I
A
N
Q
M
Q
P
D
T
T
S
V
V
K
D
S
Q
V
G
T
V
N
Y
M
P
P
E
A
I
K
D
M
S
S
S
R
E
N
G
K
S
K
S
K
I
S
P
K
S
D
V
W
S
L
G
C
I
L
Y
Y
M
T
Y
G
K
T
P
F
Q
Q
I
I
N
Q
I
S
K
L
H
A
I
I
D
P
N
H
E
I
E
F
P
D
I
P
E
K
D
L
Q
D
V
L
K
C
C
L
K
R
D
P
K
Q
R
I
S
I
P
E
L
L
A
H
P
Y
V
Q
I
Q
T
H
P
V
N
Q
M
A
K
G
T
T
E
E
M
K
Y
V
L
G
Q
L
V
G
L
N
S
P
N
S
I
L
K
A
A
K
T
L
Y
E
H
Y
S
G
G
E
S
H
N
S
S
S
S
K
T
F
E
K
K
R
G
K
K
Pkinase
D-box
p85 SH2
CDK1 motif 2 - [ST]PxxK
DEG_Nend_UBRbox_2
DEG_SPOP_SBC_1
DEG_SPOP_SBC_1
S
S
T
Y
S
K
T
S
S
S
Y
S
S
T
S
S
S
S
T
S
T
S
T
S
S
T
K
Y
S
S
K
K
S
S
S
S
S
T
S
T
Y
S
R
T
T
K
K
K
T
S
T
K
S
T
T
S
T
K
S
T
S
T
T
S
K
Y
S
S
K
Y
Y
S
S
S
K
T
K
K
K
M
S
T
S
S
S
S
S
S
S
S
K